About Me
I am Selin Cildir, a Turkish-Australian scientist-in-training with a rich and diverse background shaped by experiences across Türkiye, Italy, Singapore, and Australia. I am currently a Master of Research student at Adelaide University (Australia), working on the genetic architecture of lipoedema—a chronic and complex adipose tissue disorder whose multifactorial nature and poorly understood biological mechanisms make it an important target for genomic research. I hold a Bachelor of Science from Flinders University (Australia), where I majored in molecular biology and genetics and minored in computer science, graduating with a GPA of 6.77 out of 7.00.
My academic journey began with an undergraduate degree in Textile Engineering in Türkiye, followed by professional experiences, which included more than seven years in administrative roles across academia, industry, and government in multiple countries. These diverse experiences were more than career steps; they were transformative. They cultivated creativity, adaptability, resilience, and strong problem‑solving skills. Each chapter taught me something meaningful and brought me closer to a deeper self‑understanding—one that reflects both who I am and what I aspire to contribute.
Ultimately, this path led me to academia, where I discovered my passion for human biology and bioinformatics—a field that excites me, challenges me, and allows me to make a meaningful impact. Today, my research interests continue to expand into transcriptomics, genomics, and epigenomics. I am eager to deepen my expertise in these areas through a higher degree by research.
Balancing motherhood and academic pursuits, I am inspired daily by the opportunities to grow, learn, and contribute. As I navigate this path, I hold onto a guiding principle that has shaped my journey: "Every challenge I have faced has been an opportunity to grow, and every setback has been a setup for a greater comeback."
Projects
Genetic Architecture of Lipoedema: Rare-Variant Mapping across Lymphatic Development, Connective-Tissue Biology, and Adipose Distribution
Summary: This project investigates the genetic basis of lipoedema, a chronic and complex adipose‑tissue disorder characterised by disproportionate, painful fat accumulation and frequently associated with lymphatic and connective‑tissue abnormalities. Despite its prevalence and clinical burden, the molecular mechanisms underlying lipoedema remain poorly defined. The overarching aim of this research is to advance foundational understanding of the disease's genetic architecture and identify biological pathways that may contribute to its development and progression. This work is undertaken as part of my Master of Research at Adelaide University within the College of Health and Medical Sciences.
Cloud-Integrated Building Management System for Environmental Monitoring in Medical Laboratories Using Node-RED
Summary: As part of a Cloud and Distributed Computing course at Flinders University, I developed a cloud-integrated Building Management System (BMS) tailored for medical laboratory environments using Node-RED. This system simulates temperature, humidity and air-quality readings, validates and classifies them against safety thresholds, and then seamlessly logs and visualises the results while triggering alerts when conditions fall outside acceptable ranges.
Investigating Immune Function in IKKα: T and B Cell Profiling in Health and Disease via Genetic Demultiplexing of scRNA-Seq
Summary: This study employed single-cell RNA sequencing (scRNA-seq) and genetic demultiplexing to investigate immune function in individuals with the G167R homozygous germline mutation in the IKKα (CHUK) gene. The pipeline involved STAR for bulk RNA-seq read alignment, VarDict for SNP calling from bulk RNA-seq, and cellSNP-lite for SNP calling from scRNA-seq. Vireo was then used to demultiplex pooled scRNA-seq samples based on the detected SNPs.
Smart Manufacturing Dashboard: An Intuitive Web App for Monitoring and Managing Factory Operations
Summary: Developed a web-based dashboard for real-time monitoring and management of factory operations, designed for Administrators, Factory Managers, Production Operators, and Auditors. The platform provides CRUD (Create, Read, Update, Delete) functionalities for managing machines, jobs, and maintenance requests, featuring real-time alerts and performance analytics to support data-driven decision-making.
Research Interests
- Transcriptomics
- Genomics
- Epigenomics
Publications & Awards
- Catak MC, Surucu N, Bayram Catak F, Kara A, Cildir S, Babayeva R, Kayaoglu B, Bulutoglu A, Erman B, Karakus IS, Al-Shaibi A, Hubrack S, Karabiber E, Celebi Celik F, Akgun G, Baser D, Bilgic Eltan S, Sefer AP, Bozkurt S, Ozturk N, Kiykim A, Aydogmus C, Genel F, Gulez N, Yucel E, Yildiran A, Metin A, Karakoc-Aydiner E, Ozen A, Gursel M, Cildir G, Lo B, Baris S. "Abatacept Restores Dysregulated Transcriptomic and Proteomic Profiling in LRBA Deficiency and CTLA-4 Insufficiency." Journal of Allergy and Clinical Immunology (JACI) (IF: 11.2), 2025 Sep 16:S0091-6749(25)00946-7. DOI: 10.1016/j.jaci.2025.08.027
- May 2025: Chancellor's Letter of Commendation for Academic Excellence — Flinders University, Australia. Awarded to students who demonstrate outstanding academic achievement and rank among the top performers in their course based on exceptional GPA.
- 2024/2025: Fuss Family Summer Vacation Top Up Scholarship (AU$800). Project: "Investigating Immune Function in IKKα: T and B Cell Profiling in Health and Disease via Genetic Demultiplexing of scRNA-Seq".
- Jan–Feb 2025: UniSA Vacation Research Scholarship (AU$3000, 8 weeks). Project: "Investigating Immune Function in IKKα: T and B Cell Profiling in Health and Disease via Genetic Demultiplexing of scRNA-Seq".
- 2024: Student Essay Award, 2nd Place — "From Evolution to AI Revolution: The Growing Child of Genetics". 19th Annual Symposium of the Human Genetics Society of Australasia (HGSA), SA Branch.
- 2024: Outstanding Academic Achievement in Bachelor of Science (Flinders University 2024 Cohort). Eligibility to join Golden Key International Honour Society based on achieving a top 15% ranking in the chosen field of study.
- 2008: Erasmus Student Exchange Scholarship (4500 EUR). Selected for a prestigious Erasmus Exchange Program to study at Politecnico di Torino in Italy for one semester. Sole representative from the Textile Engineering department at Ege University, Turkiye, securing the scholarship based on outstanding academic performance and English language exam results.
Education
Degree Highlights:
- Human Bioscience
- Biochemistry
- Molecular Biology
- Genetics and Evolution
- DNA to Genome
- Protein to Proteome
- Disease and Immunology
- Bioinformatics
- Biostatistics
- Computer Programming I (Java)
- Computational Intelligence
- Computer Programming II (C++)
- Neural Networks and Machine Learning
- Cloud and Distributed Computing
- Human Factors for Interactive and Web-based Systems
Professional Memberships
- ABACBS - Australian Bioinformatics and Computational Biology Society
- COMBINE - Australian Computational Biology and Bioinformatics Student Society
- WiSE - Women in Science and Engineering, Flinders University
- Golden Key International Honour Society